Microsoft has launched the full and final version of Windows OneCare that includes two-way firewall, antivirus, antispyware and backup software. OneCare also handles routine maintenance tasks such as defragmenting the hard disk and cleaning up unused temporary files.

Though the name says Windows Live, this is actually a desktop software but setting up Windows Live OneCare on your computer requires IE
In order to complete installation of Windows Live OneCare, you must be running Internet Explorer 6 or later as your Web browser. Please switch to Internet Explorer and then restart Setup by typing http://www.windowsonecare.com/purchase into the browser address field.
Windows Live OneCare configures your computer to automatically download and install Windows and Office updates from Microsoft Update website.

Windows Live OneCare is priced at $49.95 per year for up to three computers. A 90 day trial version is also available. These are some tough times for McAfee and Symantec.